APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (HLG-HM40GTC)

  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G&B2M&Peptide (RIIPRHLQL) Antibody, hFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Exact Sequence: Gly25-Thr305(HLA-G), Ile21-Met119(B2M) and RIIPRHLQL peptide

Catalog: HLG-HM40GTC

$1,150.00
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Product Description Recombinant APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly25-Thr305 (HLA-G), Ile21-Met119 (B2M) and RIIPRHLQL peptide.

Product Background

 HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.

Product Category

 Recombinant Protein

Target

 HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer
MHC Form Tetramer
Allele HLA-G

Gene/Protein ID

 P17693-1(HLA-G)&P61769(B2M)&RIIPRHLQL

Species

 Human

Exact Sequence

 Gly25-Thr305(HLA-G), Ile21-Met119(B2M) and RIIPRHLQL peptide
Molecular Weight The protein has a predicted MW of 301.2 kDa.

Activity

 Immobilized APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G&B2M&Peptide (RIIPRHLQL) Antibody, hFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

 C-His

Fluorophore

 APC

Express System

 HEK293
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G&B2M&Peptide (RIIPRHLQL) Antibody, hFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test).
Serial dilutions of Anti-LILRB2 Antibody were added into APC-equivalent Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag: Human LILRB2, mFc Tag binding reactioins. The half maximal inhibitiory concentration (IC50) is 62.7 ng/ml.

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