Biotinylated Human HLA-E*01:03&B2M&EBV LMP1 (GGDPHLPTL) Monomer Protein (MHC-HM466B)

  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Biotinylated: yes
  • Exact Sequence: Gly25-Ile305(HLA-E*01:03), Ile21-Met119(B2M) and GGDPHLPTL peptide

Catalog: MHC-HM466B

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Product Description Recombinant Biotinylated Human HLA-E*01:03&B2M&EBV LMP1 (GGDPHLPTL) Monomer Protein is expressed from HEK293 with His tag and Avi at the C-terminus.It contains Gly25-Ile305 (HLA-E*01:03), Ile21-Met119 (B2M) and GGDPHLPTL peptide.

Product Background

 Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) is expressed in germinal-center-derived, mononuclear Hodgkin (H) and multinuclear, diagnostic Reed-Sternberg (RS) cells in classical EBV-positive Hodgkin's lymphoma (cHL). LMP1 expression in EBV-negative H-cell lines results in a significantly increased number of RS cells.

Product Category

 Recombinant Protein

Target

 HLA-E*01:03&B2M&EBV LMP1 (GGDPHLPTL) Monomer
MHC Form Monomer
Allele HLA-E*01:03

Gene/Protein ID

 P13747(HLA-E*01:03)&P61769(B2M)&GGDPHLPTL

Species

 Human

Exact Sequence

 Gly25-Ile305(HLA-E*01:03), Ile21-Met119(B2M) and GGDPHLPTL peptide
Molecular Weight The protein has a predicted MW of 50.15 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.

Product Tag

 C-His-Avi

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Biotinylated Human HLA-E*01:03&B2M&EBV LMP1 (GGDPHLPTL) Monomer is greater than 95% as determined by SEC-HPLC.
Biotinylated Human HLA-E*01:03&B2M&EBV LMP1 (GGDPHLPTL) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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