Biotinylated Human IL-3 R alpha/CD123 Protein (IL3-HM1RAB)
Catalog: IL3-HM1RAB
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| Product Description | Recombinant Biotinylated Human IL-3 R alpha/CD123 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Thr19-Arg305. |
Product Background |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 subfamily.The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias. |
Product Category |
Recombinant Protein |
Target |
IL-3 R alpha/CD123 |
Gene/Protein ID |
P26951-1 |
Species |
Human |
Exact Sequence |
Thr19-Arg305 |
| Molecular Weight | The protein has a predicted MW of 35.99 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Anti-IL-3 R alpha Antibody, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-3 R alpha, His Tag with the EC50 of 9.9ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Immobilized Anti-IL-3 R alpha Antibody, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-3 R alpha, His Tag with the EC50 of 9.9ng/ml determined by ELISA. |
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The purity of Biotinylated Human IL-3 R alpha is greater than 95% as determined by SEC-HPLC. |
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Biotinylated Human IL-3 R alpha on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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