Biotinylated Human TFPI Protein (TFP-HM401B)
Catalog: TFP-HM401B
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| Product Description | Recombinant Biotinylated Human TFPI Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp29-Lys282. |
Product Background |
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and has recently been associated with breast cancer cell development. |
Product Category |
Recombinant Protein |
Target |
TFPI |
| Synonyms | LACI; TFPI1; EPI; TFI; convertin; TFPI |
Gene/Protein ID |
P10646-1 |
Species |
Human |
Exact Sequence |
Asp29-Lys282 |
| Molecular Weight | The protein has a predicted MW of 32.1 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, the IC50 value is < 0.75 nM. |
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Biotinylated Human TFPI on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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