Biotinylated Rhesus macaque HLA-G&B2M&Peptide (RIIPRHLQL) Monomer Protein (HLG-RM41CB)
Catalog: HLG-RM41CB
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| Product Description | Recombinant Biotinylated Rhesus macaque HLA-G&B2M&Peptide (RIIPRHLQL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305 (HLA-G), Ile21-Met119 (B2M) and RIIPRHLQL peptide. |
Product Background |
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition. |
Product Category |
Recombinant Protein |
Target |
HLA-G&B2M&Peptide (RIIPRHLQL) Monomer |
| MHC Form | Monomer |
Gene/Protein ID |
O02948(HLA-G)&Q6V7J5(B2M)&RIIPRHLQL |
Species |
Rhesus macaque |
Exact Sequence |
Gly25-Thr305(HLA-G), Ile21-Met119(B2M) and RIIPRHLQL peptide |
| Molecular Weight | The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Biotinylated Rhesus macaque HLA-G&B2M&Peptide (RIIPRHLQL), His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Rhesus macaque LILRB1, hFc Tag with the EC50 of 75.8ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Liquid |
| Shipping | Shipped with dry ice. |
| Formulation | Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
| Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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Immobilized Biotinylated Rhesus macaque HLA-G&B2M&Peptide (RIIPRHLQL), His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Rhesus macaque LILRB1, hFc Tag with the EC50 of 75.8ng/ml determined by ELISA. |
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The purity of Biotinylated Rhesus macaque HLA-G&B2M&Peptide (RIIPRHLQL) Monomer is greater than 95% as determined by SEC-HPLC. |
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Biotinylated Rhesus macaque HLA-G&B2M&Peptide (RIIPRHLQL) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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