Canine EMMPRIN/CD147 Protein (EPN-DM147)
Catalog: EPN-DM147
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| Product Description | Recombinant Canine EMMPRIN/CD147 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala22-Arg205. |
Product Background |
CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiological and pathological processes including wound healing, inflammatory diseases, and cancer. CD147 is a diagnostic and therapeutic target in cancer and inflammatory diseases, either directly or indirectly, by targeting CD147 partners. |
Product Category |
Recombinant Protein |
Target |
EMMPRIN/CD147 |
Gene/Protein ID |
XP_533964.2 |
Species |
Canine |
Exact Sequence |
Ala22-Arg205 |
| Molecular Weight | The protein has a predicted MW of 21.54 kDa. Due to glycosylation, the protein migrates to 30-45 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Canine EMMPRIN is greater than 95% as determined by SEC-HPLC. |
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Canine EMMPRIN on Tris-Bis PAGE under reduced condition. The purity is greater than 90%. |
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