Canine ICAM-1/CD54 Protein (ICM-DM101)
Catalog: ICM-DM101
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| Product Description | Recombinant Canine ICAM-1/CD54 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln25-Asn476. |
Product Background |
Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and in animal models of atherosclerosis. |
Product Category |
Recombinant Protein |
Target |
ICAM-1/CD54 |
Gene/Protein ID |
P33729 |
Species |
Canine |
Exact Sequence |
Gln25-Asn476 |
| Molecular Weight | The protein has a predicted MW of 51.08 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Canine ICAM-1 is greater than 95% as determined by SEC-HPLC. |
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Canine ICAM-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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