Cynomolgus CD3E&CD3G/CD3 epsilon&CD3 gamma Protein (CD3-CM102)
Catalog: CD3-CM102
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| Product Description | Recombinant Cynomolgus CD3E&CD3G/CD3 epsilon&CD3 gamma Protein is expressed from HEK293 with His tag and Flag tag at the C-Terminus.It contains Gln22-Asp117(CD3E) & Gln23-Thr113(CD3G). |
Product Background |
T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. |
Product Category |
Recombinant Protein |
Target |
CD3E&CD3G/CD3 epsilon&CD3 gamma |
Gene/Protein ID |
Q95LI5.2(CD3E)&Q95LI7(CD3G) |
Species |
Cynomolgus |
Exact Sequence |
Gln22-Asp117(CD3E) & Gln23-Thr113(CD3G) |
| Molecular Weight | The protein has a predicted MW of 11.93 kDa (CD3E) and 11.52 kDa (CD3G). Due to glycosylation, the protein migrates to 13-23 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Cynomolgus CD3E&CD3G, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CD3 Antibody, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His-Flag |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Liquid |
| Shipping | Shipped with dry ice. |
| Formulation | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
| Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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Immobilized Cynomolgus CD3E&CD3G, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CD3 Antibody, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA. |
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The purity of Cynomolgus CD3E&CD3G is greater than 90% as determined by SEC-HPLC. |
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Cynomolgus CD3E&CD3G on Tris-Bis PAGE under reduced condition. The purity is greater than 90%. |
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