Cynomolgus DLL3 Protein (DLL-CM113)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE
Activity: Immobilized Cynomolgus DLL3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 2.3ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Ala27-Arg488

Catalog: DLL-CM113

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Product Description	Recombinant Cynomolgus DLL3 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala27-Arg488.
Product Background	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).
Product Category	Recombinant Protein

Target	DLL3
Gene/Protein ID	A0A2K5WSR1
Species	Cynomolgus
Exact Sequence	Ala27-Arg488
Molecular Weight	The protein has a predicted MW of 49.21 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Cynomolgus DLL3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 2.3ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 20mM Tris, 200mM NaCl, 200mM L-arginine (pH 8.5). Normally 8% trehalose / 8% mannitol is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Cynomolgus DLL3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 2.3ng/ml determined by ELISA.
	Cynomolgus DLL3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.