Cynomolgus FcRH5/FcRL5 Protein (FCR-CM101)
Catalog: FCR-CM101
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| Product Description | Recombinant Cynomolgus FcRH5/FcRL5 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln16-Gly851. |
Product Background |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
Product Category |
Recombinant Protein |
Target |
FcRH5/FcRL5 |
Gene/Protein ID |
XP_005541423.2 |
Species |
Cynomolgus |
Exact Sequence |
Gln16-Gly851 |
| Molecular Weight | The protein has a predicted MW of 92.13 kDa. Due to glycosylation, the protein migrates to 100-130 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Cynomolgus FcRH5 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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