Cynomolgus FGFR2 beta (IIIb) Protein (FGF-CM1BB)
Catalog: FGF-CM1BB
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| Product Description | Recombinant Cynomolgus FGFR2 beta (IIIb) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro154-Lys368. |
Product Background |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha- isoform, or only IgII and IgIII, referred to as the beta- isoform. |
Product Category |
Recombinant Protein |
Target |
FGFR2 alpha (IIIb) |
| Synonyms | Fibroblast growth factor receptor 2；FGFR-2；KGFR；K-sam；Keratinocyte growth factor receptor；CD332；BEK；KSAM |
Gene/Protein ID |
A0A2K5TL84-1 |
Species |
Cynomolgus |
Exact Sequence |
Pro154-Lys368 |
| Molecular Weight | The protein has a predicted MW of 26.2 kDa. Due to glycosylation, the protein migrates to 50-68 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Cynomolgus FGFR2 beta (IIIb) , His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-FGFR2 (IIIb) Antibody, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Immobilized Cynomolgus FGFR2 beta (IIIb) , His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-FGFR2 (IIIb) Antibody, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA. |
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The purity of Cynomolgus FGFR2 beta (IIIb) is greater than 95% as determined by SEC-HPLC. |
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Cynomolgus FGFR2 beta (IIIb) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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