Cynomolgus IGFBP2 Protein (IGF-CM102)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Gly33-Gln325

Catalog: IGF-CM102

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Product Description Recombinant Cynomolgus IGFBP2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly33-Gln325.

Product Background

 Insulin-like growth factor (IGF) binding protein 2 (IGFBP2) was discovered and identified as an IGF system regulator, controlling the distribution, function, and activity of IGFs in the pericellular space. IGFBP2 is a developmentally regulated gene that is highly expressed in embryonic and fetal tissues and markedly decreases after birth. Aberrant expression of IGFBP2 in cancer acts as a hub of an oncogenic network, integrating multiple cancer signaling pathways and serving as a potential therapeutic target for cancer treatment.

Product Category

 Recombinant Protein

Target

 IGFBP2

Gene/Protein ID

 A0A2K5WZA2

Species

 Cynomolgus

Exact Sequence

 Gly33-Gln325
Molecular Weight The protein has a predicted MW of 32.83 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result.

Product Tag

 C-His

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Cynomolgus IGFBP2 is greater than 95% as determined by SEC-HPLC.
Cynomolgus IGFBP2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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