Cynomolgus MERTK/Mer Protein (MEK-CM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Ala23-Ile507

Catalog: MEK-CM101

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Product Description Recombinant Cynomolgus MERTK/Mer Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala23-Ile507.

Product Background

 MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans.

Product Category

 Recombinant Protein

Target

 MERTK/Mer

Gene/Protein ID

 XP_005575320.2

Species

 Cynomolgus

Exact Sequence

 Ala23-Ile507
Molecular Weight The protein has a predicted MW of 53.85 kDa. Due to glycosylation, the protein migrates to 58-115 kDa based on Tris-Bis PAGE result.

Product Tag

 C-His

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Cynomolgus MERTK is greater than 95% as determined by SEC-HPLC.
Cynomolgus MERTK on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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