Cynomolgus NKp46/NCR1/CD335 Protein (NKP-CM146)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus NKp46, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-NKp46 Antibody, hFc Tag with the EC50 of 11.4ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Pro22-Asn254

Catalog: NKP-CM146

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Product Description Recombinant Cynomolgus NKp46/NCR1/CD335 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro22-Asn254.

Product Background

NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.

Product Category

Recombinant Protein

Target

NKp46/NCR1/CD335
Synonyms CD335; Ly94; NCR1; NKp46; MAR-1; NKP46FLJ99094

Gene/Protein ID

Q95JB9

Species

Cynomolgus

Exact Sequence

Pro22-Asn254
Molecular Weight The protein has a predicted MW of 27.4 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Cynomolgus NKp46, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-NKp46 Antibody, hFc Tag with the EC50 of 11.4ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in 20mM Tris, 150mM NaCl, 100mM L-arginine (pH 8.2). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Cynomolgus NKp46, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-NKp46 Antibody, hFc Tag with the EC50 of 11.4ng/ml determined by ELISA.
The purity of Cynomolgus NKp46 is greater than 95% as determined by SEC-HPLC.
Cynomolgus NKp46 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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