Cynomolgus/Rhesus macaque TIGIT Protein (TIG-CM110)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus/Rhesus macaque TIGIT, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-TIGIT Antibody, hFc Tag with the EC50 of 14.1ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Met22-Ile141

Catalog: TIG-CM110

$270.00
Size:

Order now get it on

Product Description Recombinant Cynomolgus/Rhesus macaque TIGIT Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Met22-Ile141.

Product Background

TIGIT, also called Vstm3, Vsig9, and WUCAM, is a transmembrane protein in the CD28 family of the Ig superfamily proteins.IGIT is expressed at low levels on peripheral memory and regulatory CD4 T-cells and NK cells and is up-regulated following activation of these cells.

Product Category

Recombinant Protein

Target

TIGIT
Synonyms TIGIT; VSIG9; VSTM3; WUCAM

Gene/Protein ID

XP_015300911.1

Species

Cynomolgus/Rhesus macaque

Exact Sequence

Met22-Ile141
Molecular Weight The protein has a predicted MW of 14.4 kDa. Due to glycosylation, the protein migrates to 18-25 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Cynomolgus/Rhesus macaque TIGIT, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-TIGIT Antibody, hFc Tag with the EC50 of 14.1ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Cynomolgus/Rhesus macaque TIGIT, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-TIGIT Antibody, hFc Tag with the EC50 of 14.1ng/ml determined by ELISA.
The purity of Cynomolgus/Rhesus macaque TIGIT is greater than 95% as determined by SEC-HPLC.
Cynomolgus/Rhesus macaque TIGIT on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

You may also be interested in