Cynomolgus TIM-1/HAVCR1 Protein (TIM-CM101)
Catalog: TIM-CM101
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| Product Description | Recombinant Cynomolgus TIM-1/HAVCR1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val23-Gly342. |
Product Background |
Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic cells protects the kidney after acute injury by downregulating innate immunity and inflammation. |
Product Category |
Recombinant Protein |
Target |
TIM-1/HAVCR1 |
Gene/Protein ID |
A0A2K5WXJ6 |
Species |
Cynomolgus |
Exact Sequence |
Val23-Gly342 |
| Molecular Weight | The protein has a predicted MW of 35.25 kDa. Due to glycosylation, the protein migrates to 100-150 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Cynomolgus TIM-1 is greater than 95% as determined by SEC-HPLC. |
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Cynomolgus TIM-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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