Human ASPH Protein (ASP-HE101)
Catalog: ASP-HE101
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Product Description | Recombinant Human ASPH Protein is expressed from E.coli with His tag at the N-Terminus.It contains Ile341-Ile758. |
Product Background |
Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis. |
Product Category |
Recombinant Protein |
Target |
ASPH |
Synonyms | Aspartate beta-hydroxylase; ASP beta-hydroxylase; Asph; Bah |
Gene/Protein ID |
Q12797-1 |
Species |
Human |
Exact Sequence |
Ile341-Ile758 |
Molecular Weight | The protein has a predicted MW of 49.2 kDa same as Tris-Bis PAGE result. |
Product Tag |
N-His |
Express System |
E.coli |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Liquid |
Shipping | Shipped with dry ice. |
Formulation | Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl (pH 7.4). |
Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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