Human B2M/beta 2-Microglobulin Protein (B2M-HM201)
Catalog: B2M-HM201
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| Product Description | Recombinant Human B2M/beta 2-Microglobulin Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile21-Met119. |
Product Background |
To assess whether beta-2 microglobulin (B2M) has effects on articular chondrocytes that would implicate B2M involvement in osteoarthritis (OA) pathogenesis.The average B2M level in OA synovial fluid is significantly higher than that found in normal synovial fluid. B2M is highly expressed in OA cartilage and synovial fluid compared to normal, and suggest that B2M may have effects on chondrocyte function that could contribute to OA pathogenesis. |
Product Category |
Recombinant Protein |
Target |
B2M/beta 2-Microglobulin |
| Synonyms | Beta-2-microglobulin；B2M |
Gene/Protein ID |
P61769-1 |
Species |
Human |
Exact Sequence |
Ile21-Met119 |
| Molecular Weight | The protein has a predicted MW of 38.4 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Human B2M is greater than 95% as determined by SEC-HPLC. |
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Human B2M on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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