Human CCR2b Protein-VLP (CCR-HM02B)

  • Express System: HEK293
  • Purity: > 95% as determined by HPLC
  • Activity: Immobilized Human CCR2b VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CCR2b Antibody, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Met1-Leu360

Catalog: CCR-HM02B

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Product Description Recombinant Human CCR2b Protein-VLP is expressed from HEK293.It contains Met1-Leu360.

Product Background

 The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. The actin-binding protein filamin A (FLNa) as a protein that associates with the carboxyl-terminal tail of CCR2B. FLNa emerges as an important protein for controlling the internalization and spatial localization of the CCR2B receptor in different dynamic membrane structures.

Product Category

 Recombinant Protein

Target

 CCR2b
Synonyms C-C CKR-2; CCR-2; CCR2; MCP-1-R; CMKBR2; CCR2

Gene/Protein ID

 P41597-2

Species

 Human

Exact Sequence

 Met1-Leu360
Molecular Weight The target protein has a predicted MW of 42.9kDa.

Activity

 Immobilized Human CCR2b VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CCR2b Antibody, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA. See testing image for detail.

Express System

 HEK293
Purity > 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in PBS, 300mM L-Arginine (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human CCR2b VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CCR2b Antibody, hFc Tag with the EC50 of 0.11ug/ml determined by ELISA.
The purity of Human CCR2b VLP is greater than 95% as determined by SEC-HPLC.

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