Human CCR8 Protein (CCR-HM208)

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Human-CCR8, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CCR8 Antibody, hFc Tag with the EC50 of 29.6ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Met1-Lys35

Catalog: CCR-HM208

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Product Description	Recombinant Human CCR8 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Met1-Lys35.
Product Background	CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection.
Product Category	Recombinant Protein

Target	CCR8
Gene/Protein ID	P51685-1
Species	Human
Exact Sequence	Met1-Lys35
Molecular Weight	The protein has a predicted MW of 30.62 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human-CCR8, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CCR8 Antibody, hFc Tag with the EC50 of 29.6ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human-CCR8, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CCR8 Antibody, hFc Tag with the EC50 of 29.6ng/ml determined by ELISA.
	The purity of Human CCR8 is greater than 95% as determined by SEC-HPLC.
	Human CCR8 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.