Human CD1A Protein (CDA-HM11A)
Catalog: CDA-HM11A
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| Product Description | Recombinant Human CD1A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp19-Val300. |
Product Background |
CD1 proteins are a family of major histocompatibility complex (MHC) class I-like antigen-presenting molecules that present lipids to T cells. The cytoplasmic tails (CTs) of all human CD1 isoforms, with the exception of CD1a, contain tyrosine-based sorting motifs, responsible for the internalization of proteins by the clathrin-mediated pathway. CD1a closer to MHC class I in its trafficking and potential antigen-loading compartments among CD1 isoforms. |
Product Category |
Recombinant Protein |
Target |
CD1A |
| Synonyms | CD1a; CD1A; CD1; FCB6; HTA1; R4; T6 |
Gene/Protein ID |
NP_001754.2 |
Species |
Human |
Exact Sequence |
Asp19-Val300 |
| Molecular Weight | The protein has a predicted MW of 33.3 kDa. Due to glycosylation, the protein migrates to 48-53 kDa and 13-14 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Human CD1A is greater than 95% as determined by SEC-HPLC. |
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Human CD1A on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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