Human CD42b/GP1BA Protein (GP1-HM1BA)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Human CD42b, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: His17-Leu531

Catalog: GP1-HM1BA

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Product Description	Recombinant Human CD42b/GP1BA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His17-Leu531.
Product Background	Absence of the CD42 complex leads to the Bernard-Soulier syndrome (BSS), which is a bleeding disorder characterized by thrombocytopenia and giant platelets. So far, mutations have been found in the genes encoding CD42a, CD42b and CD42c in patients with BSS**.
Product Category	Recombinant Protein

Target	CD42b/GP1BA
Synonyms	GP-Ib alpha; GPIb-alpha; GPIbA; GP1BA; BDPLT1; BDPLT3; BSS; CD42B; CD42b-alpha; DBPLT3; GP1B; VWDP; BP1BA; MGC34595
Gene/Protein ID	P07359
Species	Human
Exact Sequence	His17-Leu531
Molecular Weight	The protein has a predicted MW of 57.6 kDa. Due to glycosylation, the protein migrates to 110-115 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human CD42b, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human CD42b, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA.
	The purity of Human CD42b is greater than 95% as determined by SEC-HPLC.
	Human CD42b on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.