Human Complement Factor D/CFD Protein (CFD-HM201)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Activity: Immobilized Human Complement Factor D, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Complement Factor D Antibody, hFc Tag with the EC50 of 33.5ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Ile26-Ala253

Catalog: CFD-HM201

$315.00
Size:

Order now get it on

Bulk Quote | Test Sample
Product Description Recombinant Human Complement Factor D/CFD Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile26-Ala253.

Product Background

 Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.

Product Category

 Recombinant Protein

Target

 Complement Factor D/CFD
Synonyms Adipsin; C3 convertase activator; Complement factor D; CFD; PFD; DF; ADN; FACTOR D; AMBP-1; EC 3.4.21; EC 3.4.21.46

Gene/Protein ID

 P00746-1

Species

 Human

Exact Sequence

 Ile26-Ala253
Molecular Weight The protein has a predicted MW of 51.2 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.

Activity

 Immobilized Human Complement Factor D, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Complement Factor D Antibody, hFc Tag with the EC50 of 33.5ng/ml determined by ELISA. See testing image for detail.

Product Tag

 C-hFc

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human Complement Factor D, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Complement Factor D Antibody, hFc Tag with the EC50 of 33.5ng/ml determined by ELISA.
Human Complement Factor D on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

You may also be interested in

View more associated products