Human GP1BB Protein (GP1-HM2BB)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Pro27-Cys147

Catalog: GP1-HM2BB

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Product Description Recombinant Human GP1BB Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Pro27-Cys147.

Product Background

 The glycoprotein (GP) Ib-IX complex is the receptor on platelet surfaces that mediates their adhesion to subendothelium. It comprises three polypeptides (GP Ib alpha, GP Ib beta, GP IX), each of which belongs to a superfamily of proteins containing conserved leucine-rich motifs. Association between GP Ib alpha and GP Ib beta was demonstrated biochemically on immunoblots of detergent lysates of CHO alpha beta cells; electrophoresis under nonreducing conditions revealed the two subunits to be covalently linked through a disulfide bond.

Product Category

 Recombinant Protein

Target

 GP1BB
Synonyms GP-Ib beta; GPIb-beta; GPIbB; Gp1bb; BDPLT1; BS; CD42c; GP1BB; GPIbb; GPIbbeta

Gene/Protein ID

 P13224-1

Species

 Human

Exact Sequence

 Pro27-Cys147
Molecular Weight The protein has a predicted MW of 39.6 kDa. Due to glycosylation, the protein migrates to 47-50 kDa based on Tris-Bis PAGE result.

Product Tag

 C-hFc

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Human GP1BB is greater than 95% as determined by SEC-HPLC.
Human GP1BB on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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