Human HLA-G Free Heavy Chain Protein (HLG-HE41F)

  • Express System: E.coli
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Activity: Immobilized Human HLA-G Free Heavy Chain, His Tag at 2ug/ml (100ul/Well) on the. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 29.0ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Gly25-Thr305(C66S)

Catalog: HLG-HE41F

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Product Description Recombinant Human HLA-G Free Heavy Chain Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(C66S).

Product Background

 HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.

Product Category

 Recombinant Protein

Target

 HLA-G Free Heavy Chain
Synonyms HLA G antigen; sHLA-G; b2 microglobulin; HLA G; HLAG; HLA-G; MHC Class I Antigen G; MHC class Ib antigen; MHC-G; sHLA-G
Allele HLA-G

Gene/Protein ID

 P17693-1

Species

 Human

Exact Sequence

 Gly25-Thr305(C66S)
Molecular Weight The protein has a predicted MW of 35.5 kDa. The protein migrates to 36-40 kDa based on Tris-Bis PAGE result.

Activity

 Immobilized Human HLA-G Free Heavy Chain, His Tag at 2ug/ml (100ul/Well) on the. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 29.0ng/ml determined by ELISA. See testing image for detail.

Product Tag

 C-His-Avi

Express System

 E.coli
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl, 20% Glycerol (pH 8.0).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human HLA-G Free Heavy Chain, His Tag at 2ug/ml (100ul/Well) on the. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 29.0ng/ml determined by ELISA.
Human HLA-G Free heavy chain on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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