Human Hyaluronidase 2/HYAL2-Protein (HYA-HM101)
Catalog: HYA-HM101
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| Product Description | Recombinant Human Hyaluronidase 2/HYAL2-Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Met21-Gly447. |
Product Background |
Hyaluronidases, a family of enzymes that are able to degrade hyaluronic acid (HA), are employed in medicine to increase drug diffusion and reverse the effects of HA filler injections. Hyaluronidases are able to dissolve subcutaneous nodules or to correct excessive quantities of injected filler. Upregulation of hyaluronidase 2 (HYAL2), one of somatic hyaluronidase (HAase), was demonstrated in granulation tissue during the healing of equine superficial digital flexor tendon injuries. |
Product Category |
Recombinant Protein |
Target |
Hyaluronidase 2/HYAL2 |
Gene/Protein ID |
Q12891 |
Species |
Human |
Exact Sequence |
Met21-Gly447 |
| Molecular Weight | The protein has a predicted MW of 49.22 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Human Hyaluronidase 2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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