Human IGF2R Domain 1-3 Protein (IGF-HM1RD)
Catalog: IGF-HM1RD
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| Product Description | Recombinant Human IGF2R Domain 1-3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu47-Lys468. |
Product Background |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. |
Product Category |
Recombinant Protein |
Target |
IGF2R Domain 1-3 |
Gene/Protein ID |
P11717 |
Species |
Human |
Exact Sequence |
Glu47-Lys468 |
| Molecular Weight | The protein has a predicted MW of 50.50 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Human IGF2R Domain 1-3 is greater than 95% as determined by SEC-HPLC. |
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Human IGF2R Domain 1-3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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