Human IGSF11 Protein (ISF-HM111)
Catalog: ISF-HM111
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| Product Description | Recombinant Human IGSF11 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu23-Gly241. |
Product Background |
Immunoglobulin superfamily member 11 (IgSF11), a homophilic adhesion molecule that preferentially expressed in the brain, is a dual-binding partner of the postsynaptic scaffolding protein PSD-95 and AMPA glutamate receptors (AMPARs). |
Product Category |
Recombinant Protein |
Target |
IGSF11 |
Gene/Protein ID |
Q5DX21-1 |
Species |
Human |
Exact Sequence |
Leu23-Gly241 |
| Molecular Weight | The protein has a predicted MW of 24.31 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result. |
Activity |
The affinity constant of 14.44 uM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Human B7-H5, hFc Tag captured on CM5 Chip via Protein A can bind Human IGSF11, His Tag with an affinity constant of 14.44 uM as determined in SPR assay (Biacore T200). |
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The purity of Human IGSF11 is greater than 95% as determined by SEC-HPLC. |
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Human IGSF11 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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