Human LIF R/CD118 Protein (LIF-HM20R)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Activity: Immobilized Human LIF, No Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human LIF R, hFc Tag with the EC50 of 66.8ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Gln45-Ser833

Catalog: LIF-HM20R

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Product Description Recombinant Human LIF R/CD118 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln45-Ser833.

Product Background

The leukemia inhibitory factor receptor (LIF-R) subunit is a component of cell-surface receptor complexes for the multifunctional cytokines, LIF, cardiotrophin-1, ciliary neurotrophic factor, and human oncostatin M. The structure of the human LIF-R gene is similar to that of the mouse gene. The transmembrane receptor is encoded by 19 exons.

Product Category

Recombinant Protein

Target

LIF R/CD118
Synonyms FLJ99923; SJS2; STWS; SWS; LIFR; CD118; FLJ98106

Gene/Protein ID

P42702-1

Species

Human

Exact Sequence

Gln45-Ser833
Molecular Weight The protein has a predicted MW of 116.1 kDa. Due to glycosylation, the protein migrates to 120-160 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human LIF, No Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human LIF R, hFc Tag with the EC50 of 66.8ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCL, 200mM L-arginine, 5mM DTT.
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human LIF, No Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human LIF R, hFc Tag with the EC50 of 66.8ng/ml determined by ELISA.
Human LIF R on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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