Human RET-Protein (RET-HM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
  • Exact Sequence: Leu29-Arg635

Catalog: RET-HM101

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Product Description Recombinant Human RET-Protein is expressed from HEK293 with His tag at the C-Terminus.; It contains Leu29-Arg635.

Product Background

 RET is a proto-oncogene encoding a receptor tyrosine kinase. RET regulates key aspects of cellular proliferation, differentiation and survival. The activation of RET via gene fusions or point mutations is closely related to lung, thyroid and other cancers.

Product Category

 Recombinant Protein

Target

 RET

Gene/Protein ID

 P07949-1

Species

 Human

Exact Sequence

 Leu29-Arg635
Molecular Weight The protein has a predicted MW of 68.87 kDa. Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.

Product Tag

 C-His

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin Less than 1 EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Human RET is greater than 95% as determined by SEC-HPLC.
Human RET-on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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