Human Serpin F1/PEDF Protein (SF1-HM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Gln20-Pro418

Catalog: SF1-HM101

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Product Description Recombinant Human Serpin F1/PEDF Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln20-Pro418.

Product Background

 Pigment epithelium-derived factor (PEDF) is an important antiangiogenic and antitumorigenic factor in a variety of cancer forms, including pancreatic cancer. PEDF is mainly secreted as a soluble monomeric glycoprotein. In human pancreatic cancer PEDF levels are decreased, both in the tissue and serum. The decrease is associated with increased tumor angiogenesis, fibrosis, inflammation, autophagy, occurrence of liver metastasis and worse prognosis.

Product Category

 Recombinant Protein

Target

 Serpin F1/PEDF
Synonyms PEDF; EPC-1; Serpin F1; SERPINF1; PIG35

Gene/Protein ID

 P36955

Species

 Human

Exact Sequence

 Gln20-Pro418
Molecular Weight The protein has a predicted MW of 45.5 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

Product Tag

 C-His

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl (pH 8.0).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Human Serpin F1/PEDF is greater than 95% as determined by SEC-HPLC.
Human Serpin F1/PEDF on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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