Human SETD7-Protein (SED-HM107)
Catalog: SED-HM107
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| Product Description | Recombinant Human SETD7-Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Lys366. |
Product Background |
SETD7 is a methyltransferase that specifically catalyzes the monomethylation of lysine 4 on histone H3. A variety of studies has revealed the role of SETD7 in posttranslational modifications of non-histone proteins. Aberrant expression of SETD7 has been associated with various diseases, including cancer. As a prognostic marker of breast cancer and a novel antioxidant promoter under oxidative stress in breast cancer, SETD7 is considered a good target for the development of new epigenetic drugs. |
Product Category |
Recombinant Protein |
Target |
SETD7 |
Gene/Protein ID |
NP_085151.1 |
Species |
Human |
Exact Sequence |
Met1-Lys366 |
| Molecular Weight | The protein has a predicted MW of 41.68 kDa. The protein migrates to 47-50 kDa based on Tris-Bis PAGE result. |
Product Tag |
N-His |
Express System |
E.coli |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Human SETD7-is greater than 95% as determined by SEC-HPLC. |
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Human SETD7 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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