Human Siglec-9 Protein (SIG-HM219)
Catalog: SIG-HM219
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Product Description | Recombinant Human Siglec-9 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln18-Gly348. |
Product Background |
Siglec-9 is a sialic-acid-binding lectin expressed predominantly on myeloid cells. Aberrant glycosylation occurs in essentially all types of cancers and results in increased sialylation. Thus, when the mucin MUC1 is expressed on cancer cells, it is decorated by multiple short, sialylated O-linked glycans (MUC1-ST). |
Product Category |
Recombinant Protein |
Target |
Siglec-9 |
Synonyms | CD329; CDw329; FOAP-9; OBBP-Like; Siglec-9; SIGLEC9 |
Gene/Protein ID |
Q9Y336 |
Species |
Human |
Exact Sequence |
Gln18-Gly348 |
Molecular Weight | The protein has a predicted MW of 62.8 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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