Human TACI/TNFRSF13B Protein (TAC-HM213)

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Human BAFF Trimer, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Ser2-Thr166

Catalog: TAC-HM213

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Product Description	Recombinant Human TACI/TNFRSF13B Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser2-Thr166.
Product Background	Transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) is one of the receptors of B cell activating factor of the tumor necrosis factor family (BAFF) and a proliferation-inducing ligand (APRIL). TACI is a regulator in the immune responses. TACI inhibits B cell expansion and promotes the differentiation and survival of plasma cells.
Product Category	Recombinant Protein

Target	TACI/TNFRSF13B
Synonyms	CD267; TNFRSF13B; TACI; CVID; CVID2; IGAD2; RYZN; TACI
Gene/Protein ID	O14836-1
Species	Human
Exact Sequence	Ser2-Thr166
Molecular Weight	The protein has a predicted MW of 45.3 kDa. Due to glycosylation, the protein migrates to 38-40 kDa and 50-55 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human BAFF Trimer, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human BAFF Trimer, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA.
	The purity of Human TACI is greater than 95% as determined by SEC-HPLC.
	Human TACI on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.