Human TGFBR1 Protein (TGF-HM6R1)

Express System: HEK293
Product Tag: C-mFc-Avi
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 0.35 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Exact Sequence: Leu34-Glu125

Catalog: TGF-HM6R1

Order now get it on

Bulk Quote | Test Sample

Product Description	Recombinant Human TGFBR1 Protein is expressed from HEK293 with mFc (IgG1) tag and Avi tag at the C-Terminus.It contains Leu34-Glu125.
Product Background	transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells.
Product Category	Recombinant Protein

Target	TGFBR1
Synonyms	AAT5; ACVRLK4; ALK-5; LDS1A; LDS2A; SKR4; tbetaR-I; TGFB1R1; TGF-beta RI; TGFbetaRI; TGFBR1; TGF-bRI; TGFR-1
Gene/Protein ID	P36897-1
Species	Human
Exact Sequence	Leu34-Glu125
Molecular Weight	The protein has a predicted MW of 38.2 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Tris-Bis PAGE result.
Activity	The affinity constant of 0.35 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-mFc-Avi
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Human TGFBR1, mFc Tag captured on CM5 Chip via Protein A can bind Human Mature TGF beta 1, No Tag with an affinity constant of 0.35 uM as determined in SPR assay (Biacore T200).
	The purity of Human TGFBR1 is greater than 95% as determined by SEC-HPLC.
	Human TGFBR1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.