Human TROP-2/TACSTD2 Protein (TRP-HM121)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human TROP-2, His Tag at 0.5ug/ml (100ul/Well). Dose response curve for Anti-TROP-2 Antibody, hFc Tag with the EC50 of 7.1ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Exact Sequence: His27-Thr274

Catalog: TRP-HM121

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Product Description Recombinant Human TROP-2/TACSTD2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His27-Thr274.

Product Background

Trop-2,also known as epithelial glycoprotein-1 antigen (EGP-1),is a protein that in humans is encoded by the TACSTD2 gene.Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.

Product Category

Recombinant Protein

Target

TROP-2/TACSTD2
Synonyms EGP1; EGP-1; TROP2; GA733-1; gp50; T16; TACSTD2; TROP-2; M1S1; TACD2

Gene/Protein ID

P09758

Species

Human

Exact Sequence

His27-Thr274
Molecular Weight The protein has a predicted MW of 28.9 kDa. Due to glycosylation, the protein migrates to 40-60 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human TROP-2, His Tag at 0.5ug/ml (100ul/Well). Dose response curve for Anti-TROP-2 Antibody, hFc Tag with the EC50 of 7.1ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human TROP-2, His Tag at 0.5ug/ml (100ul/Well). Dose response curve for Anti-TROP-2 Antibody, hFc Tag with the EC50 of 7.1ng/ml determined by ELISA (QC Test).
Immobilized Human TROP-2, His Tag at 0.5ug/ml (100ul/Well). Dose response curve for Anti-TROP-2 Antibody, hFc Tag with the EC50 of 7.1ng/ml / 7.2ng/ml / 7.2ng/ml determined by ELISA.
The purity of Human TROP-2 is greater than 95% as determined by SEC-HPLC.
Human TROP-2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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