Human ULBP-2 Protein (ULB-HM202)
Catalog: ULB-HM202
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Product Description | Recombinant Human ULBP-2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly26-Ser216. |
Product Background |
ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity. |
Product Category |
Recombinant Protein |
Target |
ULBP-2 |
Gene/Protein ID |
Q9BZM5 |
Species |
Human |
Exact Sequence |
Gly26-Ser216 |
Molecular Weight | The protein has a predicted MW of 48.40 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
Activity |
The affinity constant of 62.42 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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