Name: Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein (MHC-MM452)
Brand: KactusBio
SKU: MHC-MM452-100UG
Price: 341.0 USD
Availability: InStock

SEC-HPLC chromatogram of protein sample showing a sharp monomeric peak at retention time 8.663 minutes.

Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein (MHC-MM452)

Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: His23-Pro296(Qa-1b), Ile21-Met119(B2M) and AMAPRTLLL peptide

Catalog #MHC-MM452

Size

100UG

500UG

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Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein (MHC-MM452) Summary

Product Description	Recombinant Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus; It contains His23-Pro296(Qa-1b), Ile21-Met119(B2M) and AMAPRTLLL peptide.
Product Background	Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of the peptides associated with this molecule. Human histocompatibility leukocyte antigen (HLA)-E, a homologue of Qa-1b, binds similar peptides derived from human class Ia molecules and interacts with CD94/NKG2 receptors on natural killer cells.
Product Category	Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

Q1-1b&B2M&Qdm (AMAPRTLLL) Specifications

Protein	Q1-1b&B2M&Qdm (AMAPRTLLL)
Synonyms	Qdm; Qa-1b; MHC; H2-T23
MHC Form	Monomer
Allele	Qa-1b
Accession	P06339(Q1-1b)&P01887(B2M)&AMAPRTLLL
Species	Mouse
Biotinylated	no
Amino Acid Range	His23-Pro296(Qa-1b), Ile21-Met119(B2M) and AMAPRTLLL peptide
Molecular Weight	The protein has a predicted MW of 50.60 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer is greater than 95% as determined by SEC-HPLC.