Mouse Activin RIIB/ACVR2B Protein (ARB-MM12B)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse Activin RIIB, His Tag with the EC50 of 22.1ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Ser19-Thr137

Catalog: ARB-MM12B

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Product Description	Recombinant Mouse Activin RIIB/ACVR2B Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser19-Thr137.
Product Background	ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myostatin (MSTN), growth differentiation factor 11 (GDF11), and bone morphogenetic protein 9 (BMP9).
Product Category	Recombinant Protein

Target	Activin RIIB/ACVR2B
Gene/Protein ID	P27040-1
Species	Mouse
Exact Sequence	Ser19-Thr137
Molecular Weight	The protein has a predicted MW of 14.78 kDa. Due to glycosylation, the protein migrates to 30-50 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse Activin RIIB, His Tag with the EC50 of 22.1ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse Activin RIIB, His Tag with the EC50 of 22.1ng/ml determined by ELISA.
	The purity of Mouse Activin RIIB is greater than 95% as determined by SEC-HPLC.
	Mouse Activin RIIB on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.