Mouse AREG Protein (AEG-MM201)
Catalog: AEG-MM201
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| Product Description | Recombinant Mouse AREG Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Val100-Ala248. |
Product Background |
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor. |
Product Category |
Recombinant Protein |
Target |
AREG |
| Synonyms | Amphiregulin; AR; SDGF; AREG; AREGB; CRDGF; MGC13647 |
Gene/Protein ID |
P31955 |
Species |
Mouse |
Exact Sequence |
Val100-Ala248 |
| Molecular Weight | The protein has a predicted MW of 38.6 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result. |
Product Tag |
N-hFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Mouse AREG is greater than 95% as determined by SEC-HPLC. |
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Mouse AREG on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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