Mouse CD19 Protein (CD1-MM119)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 90% as determined by Tris-Bis PAGE
  • Exact Sequence: Arg19-Gly287

Catalog: CD1-MM119

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Product Description Recombinant Mouse CD19 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg19-Gly287.

Product Background

CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses.Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2 stores.

Product Category

Recombinant Protein

Target

CD19
Synonyms CD19; B4; CVID3; Leu-12; MGC12802

Gene/Protein ID

P25918

Species

Mouse

Exact Sequence

Arg19-Gly287
Molecular Weight The protein has a predicted MW of 30.7 kDa. Due to glycosylation, the protein migrates to 55-68 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 90% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse CD19 on Tris-Bis PAGE under reduced condition. The purity is greater than 90%.

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