Mouse CLEC-1 Protein (CLE-MM201)
Catalog: CLE-MM201
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| Product Description | Recombinant Mouse CLEC-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gln73-Gln269. |
Product Background |
C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1β production in response to A. fumigatus keratitis. |
Product Category |
Recombinant Protein |
Target |
CLEC-1 |
| Synonyms | CLEC-1; CLEC1; CLEC1A; MGC34328 |
Gene/Protein ID |
Q8BWY2 |
Species |
Mouse |
Exact Sequence |
Gln73-Gln269 |
| Molecular Weight | The protein has a predicted MW of 50.4 kDa. Due to glycosylation, the protein migrates to 66-68 kDa based on Tris-Bis PAGE result. |
Product Tag |
N-hFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Mouse CLEC-1 is greater than 95% as determined by SEC-HPLC. |
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Mouse CLEC-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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