Mouse CLEC9A Protein (CLE-MM29A)

  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Lys57-Ile264

Catalog: CLE-MM29A

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Product Description Recombinant Mouse CLEC9A Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Lys57-Ile264.

Product Background

 CLEC9A expression was significantly higher in psoriatic skin compared with healthy donor. In psoriatic skin and PsA ST, CLEC9A() cells were in close proximity to TUNEL() cells. SF CLEC9A levels were significantly lower compared with paired PsA serum. Adalimumab treatment did not affect CLEC9A serum level and skin expression. The downregulation of synovial CLEC9A might be associated with a novel mechanism by which anti-TNF therapy might reduce CD8-mediated inflammation in PsA patients.

Product Category

 Recombinant Protein

Target

 CLEC9A
Synonyms CD370; CLEC9A; 9830005G06Rik; DNGR-1; HEEE9341; UNQ9341

Gene/Protein ID

 NP_001192292.1

Species

 Mouse

Exact Sequence

 Lys57-Ile264
Molecular Weight The protein has a predicted MW of 50.9 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

Product Tag

 N-hFc

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse CLEC9A is greater than 95% as determined by SEC-HPLC.
Mouse CLEC9A on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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