Mouse CPM Protein (CPM-MM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Leu18-Ser423

Catalog: CPM-MM101

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Product Description Recombinant Mouse CPM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu18-Ser423.

Product Background

Carboxypeptidase M (CPM) is a glycosylphosphatidylinositol anchored enzyme that plays an important role in the kallikrein-kinin system (KKS). CPM catalytic domain hydrolyzes Arg from C-terminal peptides (i.e., bradykinin and kallidin), generating des-Arg-kinins, the agonists of B1 receptor (B1R).

Product Category

Recombinant Protein

Target

CPM

Gene/Protein ID

Q80V42-1

Species

Mouse

Exact Sequence

Leu18-Ser423
Molecular Weight The protein has a predicted MW of 47.51 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse CPM is greater than 95% as determined by SEC-HPLC.
Mouse CPM on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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