Mouse CXCL13/BCA-1 Protein (CXC-MM113)

  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Exact Sequence: Ile22-Ala109

Catalog: CXC-MM113

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Product Description Recombinant Mouse CXCL13/BCA-1 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ile22-Ala109.

Product Background

Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.

Product Category

Recombinant Protein

Target

CXCL13/BCA-1
Synonyms ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13

Gene/Protein ID

O55038

Species

Mouse

Exact Sequence

Ile22-Ala109
Molecular Weight The protein has a predicted MW of 11.7 kDa. Due to glycosylation, the protein migrates to 16-20 kDa based on Tris-Bis PAGE result.

Product Tag

N-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in 50mM Tris, 500mM NaCl (pH 7.5).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse CXCL13 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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