Mouse CXCL13/BCA-1 Protein (CXC-MM213)

  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Ile22-Ala109

Catalog: CXC-MM213

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Product Description Recombinant Mouse CXCL13/BCA-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ile22-Ala109.

Product Background

 Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.

Product Category

 Recombinant Protein

Target

 CXCL13/BCA-1
Synonyms ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13

Gene/Protein ID

 O55038

Species

 Mouse

Exact Sequence

 Ile22-Ala109
Molecular Weight The protein has a predicted MW of 37.1 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

Product Tag

 N-hFc

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in 50mM Tris, 500mM NaCl (pH 7.5).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Mouse CXCL13 is greater than 95% as determined by SEC-HPLC.
Mouse CXCL13 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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