Mouse EDA2R Protein (EDA-MM22R)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Met1-Thr138

Catalog: EDA-MM22R

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Product Description Recombinant Mouse EDA2R Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Met1-Thr138.

Product Background

 EDA2R is a member of the large family of tumor necrosis factor receptor (TNFR). Previous studies suggested that EDA2R expression might be increased in the kidneys of diabetic mice. High glucose increases EDA2R expression in kidney cells and that EDA2R induces podocyte apoptosis and dedifferentiation in high glucose milieu partially through enhanced ROS generation.

Product Category

 Recombinant Protein

Target

 EDA2R

Gene/Protein ID

 Q8BX35

Species

 Mouse

Exact Sequence

 Met1-Thr138
Molecular Weight The protein has a predicted MW of 42.15 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

Product Tag

 C-hFc

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse EDA2R is greater than 95% as determined by SEC-HPLC.
Mouse EDA2R on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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