Mouse IL-5 R alpha/CD125 Protein (ILR-MM15R)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 0.495 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Exact Sequence: Asp18-His339

Catalog: ILR-MM15R

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Product Description Recombinant Mouse IL-5 R alpha/CD125 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp18-His339.

Product Background

Interleukin‑5 Receptor alpha (IL‑5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5.

Product Category

Recombinant Protein

Target

IL-5 R alpha
Synonyms CD125; CDw125CD125; HSIL5R3; IL-5 R alpha; IL-5R subunit alpha; IL5R; IL5RA; IL-5Ra; MGC26560

Gene/Protein ID

P21183

Species

Mouse

Exact Sequence

Asp18-His339
Molecular Weight The protein has a predicted MW of 37.7 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

Activity

The affinity constant of 0.495 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse IL-5 R alpha, His Tag immobilized on CM5 Chip can bind Mouse IL-5, His Tag with an affinity constant of 0.495 uM as determined in SPR assay (Biacore T200).
The purity of Mouse IL-5 R alpha is greater than 95% as determined by SEC-HPLC.
Mouse IL-5 R alpha on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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