Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (ITG-MM1LB)
Catalog: ITG-MM1LB
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| Product Description | Recombinant Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail. |
Product Background |
Integrin αLβ2 is one member of the integrin family and also called leukocyte function-associated antigen-1 (LFA-1). It is widely expressed on T lymphocytes and controls the function and, in particular, the migration of immune cells[1]. Active αLβ2 can bind ICAM1/CD54, ICAM2, ICAM3 and JAM1[2]. |
Product Category |
Recombinant Protein |
Target |
Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer |
Gene/Protein ID |
P24063-1(ITGAL)&P11835(ITGB2) |
Species |
Mouse |
Exact Sequence |
Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail |
| Molecular Weight | The protein has a predicted MW of 123.30 kDa (ITGAL) and 79.60 kDa (ITGB2). Due to glycosylation, the protein migrates to 160-180 kDa (ITGAL) and 90-105 kDa (ITGB2) based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Mouse ITGAL&ITGB2 is greater than 95% as determined by SEC-HPLC. |
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Mouse ITGAL&ITGB2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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