Mouse MEPE Protein (MEP-MM101)
Catalog: MEP-MM101
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| Product Description | Recombinant Mouse MEPE Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala25-Asp441. |
Product Background |
Matrix extracellular phosphoglycoprotein (MEPE) is expressed in bone and teeth where it has multiple functions. The C-terminus of MEPE contains a mineral-binding, acidic serine- and aspartate-rich motif (ASARM) that is also present in other noncollagenous proteins of mineralized tissues.MEPE-derived ASARM peptides function in phosphate homeostasis and direct inhibition of bone mineralization in a phosphorylation-dependent manner. |
Product Category |
Recombinant Protein |
Target |
MEPE |
| Synonyms | OF45; MEPE; Osteoregulin |
Gene/Protein ID |
Q8K4L6 |
Species |
Mouse |
Exact Sequence |
Ala25-Asp441 |
| Molecular Weight | The protein has a predicted MW of 45.3 kDa. The protein is cleaved into 2 chains and due to glycosylation, it migrates to 45-60 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Mouse MEPE on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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